Authors
Hiroya Iida, Hiroji Shinkawa, Hisashi Kosaka, Masaki Ueno, Haruki Mori, Koji Komeda, Satoshi Yasuda, Masahiko Kinoshita, Shinya Hayami, Masaji Tani, Masaki Kaibori, Shoji Kubo
Published in
Asian Pacific journal of cancer prevention : APJCP. Volume 27. Issue 6. Pages 2043-2052. Jun 01, 2026. Epub Jun 01, 2026.
Abstract
The effect of previous biliary reconstruction (BR) or endoscopic sphincterotomy (EST) on post-hepatectomy bile leakage and abscess formation remains controversial. This study aimed to investigate the incidence, clinical findings, and risk factors of postoperative abscesses in the liver resection plane in patients with such histories.
This multicenter retrospective study included 5,742 patients who underwent liver resection between 2011 and 2020 (38 with a history of BR, 44 with EST, and 5,660 with no history of biliary treatment). The incidence, clinical characteristics, and risk factors for abscess formation, as well as factors associated with prolonged healing duration (≥45 days), were analyzed.
Abscess formation was significantly more frequent in the BR (47.4%) and EST (25.0%) groups than in the non-BR/non-EST group (3.5%). Bile leakage was identified as an independent risk factor for abscess formation. Bile leakage and mixed infection both significantly more frequent in the BR group than in the non-BR/non-EST group were independent risk factors for prolonged healing duration.
Patients with a history of BR or EST are at a higher risk of postoperative abscess formation in the liver resection plane. Bile leakage plays a critical role in both abscess development and prolonged healing.
PMID:
42345150
Bibliographic data and abstract were imported from PubMed on 25 Jun 2026.
Read full publication at:
Please sign in
to see all details.
Advertisement
Stats
- Recommendations n/a n/a positive of 0 vote(s)
- Views 5
- Comments 0