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Expert Consensus on the Combined Application of Radiotherapy and Novel Systemic Agents in Breast Cancer Treatment.

Created on 25 Jun 2026

Authors

Jie Lan, Wenyi Zhou, Qiufan Zheng, Lu Cao, Wenyan Chen, Zhenyu He, Chunling Jiang, Yanchu Li, Wen Xia, Huihua Xiong, Xiaoli Yu, Jun Zhang, Jianli Zhao, Yanxia Zhao, Lei Liu, Xin Wu, Shusen Wang, Xiaobo Huang, Jing Jing

Published in

Journal of evidence-based medicine. Pages e70148. Jun 25, 2026. Epub Jun 25, 2026.

Abstract

The rapid advancement of radiotherapy techniques and systemic anticancer agents has created unprecedented opportunities to improve outcomes for breast cancer patients, while also introducing new challenges related to optimal integration and safety. This consensus, convened by the Breast Cancer Committee of the Chinese Anti-Cancer Association and Chinese Society of Clinical Oncology Breast Cancer Committee, systematically evaluated available literature through November 2025 and employed Delphi methodology to generate evidence-based recommendations for combining radiotherapy with immune checkpoint inhibitors, targeted therapies, antibody-drug conjugates and endocrine agents across disease stages. This work aims to guide clinicians toward safer and more effective integration of radiotherapy with contemporary systemic treatments, promote consistency in clinical practice, and identify priority directions for future research to refine precision radiotherapy and systemic therapy combinations in breast cancer.

PMID:
42347760
Bibliographic data and abstract were imported from PubMed on 25 Jun 2026.

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