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When Sepsis Kills: A Fatal Cascade of Invasive Group A Streptococcal Sepsis.

Created on 25 Jun 2026

Authors

N K Brulinska, M Harb, P Kiely

Published in

Irish medical journal. Volume 119. Issue 6. Pages 114. Jun 18, 2026. Epub Jun 18, 2026.

Abstract

A previously healthy 22-year-old woman presented with right groin pain, unilateral leg swelling, and dyspnoea following recent infection and minor trauma. She was hypotensive and tachycardic with a painful, mottled limb and oxygen saturations of 91%.
Investigations demonstrated lactic acidosis, coagulopathy, pulmonary emboli, visceral infarcts, and necrotising soft-tissue infection. Cultures confirmed Streptococcus pyogenes.
Despite antibiotics, emergency surgery, and advanced life support, the patient died of multiorgan failure.
iGAS infection can mimic thromboembolic disease and requires urgent recognition.

PMID:
42348317
Bibliographic data and abstract were imported from PubMed on 25 Jun 2026.

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