Authors
Jing Zeng, Xianfen Cao, Xi Yin, Qing Zhou, Jun Lyu, Xiangyin Sha
Published in
Discover oncology. Jun 25, 2026. Epub Jun 25, 2026.
Abstract
Primary ocular adnexal lymphoma (POAL) is the most common malignancy affecting para-ocular tissues, making prognosis and survival critical concerns. This study analyzed trends in five-year relative survival rates (RSR) to evaluate survival outcomes.
This retrospective study included patients diagnosed with POAL from the Surveillance, Epidemiology, and End Results database. Five-year RSR was calculated for the periods 2005-2009, 2010-2014, and 2015-2019. Data were stratified by demographic and clinical characteristics. Model-based period analysis was conducted to assess RSR trends and project RSR for 2020-2024.
The five-year RSR for POAL patients increased from 96.1% to 99.1% between 2005 and 2019, with projections suggesting continued favorable trends. RSR decreased with advancing age but improved across all age groups; for 2020-2024, RSR was projected to approach 100% for patients aged < 50 and 50-69 years, and 98.3% for those ≥ 70 years. Females consistently showed slightly higher RSR than males. White patients demonstrated steady improvement, while Black patients exhibited a fluctuating trend and other racial groups showed modest increases. Higher RSR was observed in patients with conjunctival involvement, unilateral disease, and mucosal-associated lymphoid tissue (MALT) or follicular lymphoma subtypes.
Survival for POAL patients improved between 2005 and 2019. Projected estimates for 2020-2024, while subject to inherent uncertainty, suggest continued favorable outcomes, providing useful prognostic information for clinicians and patients.
PMID:
42347900
Bibliographic data and abstract were imported from PubMed on 25 Jun 2026.
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