Redefining therapeutic horizons in thymic epithelial tumors: precision, combinations, and emerging biology.

Authors

Jennifer A Marks, Rohan Maniar, Kavitha J Ramchandran, Erica Pietroluongo, Mehmet Altan, Surbhi Singhal, Mihaela Aldea, Jonathan W Goldman, Jonathan W Reiss, Heather Wakelee, Patrick J Loehrer, Marina Chiara Garassino, Anja C Roden, Jordi Remon, Christopher S Nabel, Chul Kim

Published in

NPJ precision oncology. Jun 26, 2026. Epub Jun 26, 2026.

Abstract

Thymic epithelial tumors (TETs) are rare and diverse cancers with distinctive immune features, limited prospective evidence, and few systemic options. Their association with autoimmunity, especially thymomas, complicates treatment decisions. This review examines molecular profiling and predictive biomarkers in TET and explores new treatment strategies. We highlight priorities for future trials, global registries, and real-world data to expand access to expert, multidisciplinary care, charting a path toward precision-guided, combination-based treatments.

PMID:
42363019
Bibliographic data and abstract were imported from PubMed on 27 Jun 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.