Authors
Yufeng Lai, Yu Ma, Zhengkun Gan, Zhiming Jian, Aien Tao, Guihua Jiang
Published in
Carbohydrate research. Volume 567. Pages 110009. Jun 20, 2026. Epub Jun 20, 2026.
Abstract
Ganoderma lucidum spores are minute particles released from the substrate of Ganoderma lucidum that function as the reproductive cells of the organism. Ganoderma lucidum spores are widely recognized as a functional food. Polysaccharides are the predominant bioactive components found in G. lucidum spores and significantly contribute to their health benefits. However, the structural characteristics of these polysaccharides remain poorly understood. Recent studies have shown that these spores contain active compounds with significant pharmacological properties, including antitumor, immunomodulatory, antioxidant, cardiovascular, and hepatoprotective effects. As a result, Ganoderma lucidum spores have become a focal point in research on their development and application, particularly within biomedicine and functional foods. The methods used for extraction, isolation, and purification can significantly influence the content, purity, and structural characteristics of Ganoderma lucidum spore polysaccharides (GLSP), thereby affecting their biological activities to varying degrees. Although GLSP are important in biological research and drug discovery, comprehensive reviews on these substances, especially regarding the application of GLSP in health products, are notably lacking. This paper systematically reviews the latest research on the extraction, isolation, and purification techniques, structural characterization, and bioactivities of GLSP, both domestically and internationally, with the aim of providing a theoretical foundation for further research and product development involving GLSP.
PMID:
42365737
Bibliographic data and abstract were imported from PubMed on 29 Jun 2026.
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