Authors
Papitchaya Boonpatumpong, Thanya Sitthisettapong, Piyaporn Pultanasarn, Parichart Naruphontjirakul, Anne M Young, Piyaphong Panpisut
Published in
Dental materials journal. Jun 26, 2026. Epub Jun 26, 2026.
Abstract
This study evaluated the monomer conversion (DC), surface microhardness, elemental release, and cytotoxicity of experimental dental sealants containing monocalcium phosphate monohydrate (MCPM), strontium/fluoride-bioactive glass nanoparticles (Sr/F-BAGs), and ε-polylysine. Experimental sealants with (TS1) and without additives (TS0) were compared to commercial sealants (Clinpro and BeautiSealant). DC was measured after light-curing for 40 s. Surface microhardness and elemental release in deionized water were determined after 4-week water storage. Cell viability of the extract was also examined. TS1 exhibited a DC of 82%, significantly higher than commercial materials (65-73%, p<0.05). Surface microhardness of TS1 (14.8 VHN) was comparable to commercial sealants (p>0.05). TS1 released Ca, Sr, and P ions, while commercial materials released mainly fluoride. All materials showed >70% cell viability. The experimental dental sealant demonstrated satisfactory polymerization and mechanical properties with enhanced multi-ion release, suggesting potential for improved bioactivity of the material to help prevent caries associated with restoration and sealant (CARS).
PMID:
42366062
Bibliographic data and abstract were imported from PubMed on 29 Jun 2026.
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