Vascularized Iris Mass as Sentinel Manifestation of Syphilis in Patient with HIV Infection, Spain, 2025.

Authors

Marta Caminal-Caramés, Jaume Sánchez-Serra, Jesus Díaz-Cascajosa, Albert Saladrigas, Santiago Conversa, Jose Ignacio Vela-Segarra

Published in

Emerging infectious diseases. Volume 32. Issue 7. Pages 1163-1166.

Abstract

Vascularized iris masses are rare, yet highly suggestive of syphilis. We report a 51-year-old man in Spain with HIV infection who had painful vision loss, rash, and an iris mass. Laboratory testing confirmed syphilis; ocular manifestations resolved with intravenous ceftriaxone and penicillin. Early recognition of syphilis can prevent vision loss and neurologic complications.

PMID:
42366108
Bibliographic data and abstract were imported from PubMed on 29 Jun 2026.

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