Authors
Daniel Zeitouni, Joshua Joseph, Ashwin Sannecy, Steve Monk, Jonathan Parish, Mark Van Poppel, Scott Wait
Published in
Journal of neurosurgery. Case lessons. Volume 11. Issue 26. Jun 29, 2026. Epub Jun 29, 2026.
Abstract
Craniopharyngioma is a rare, noncancerous tumor that develops from Rathke's pouch. Gross-total resection (GTR) is essential to reduce the risk of recurrence. Once the cyst is decompressed, it can be difficult to appreciate how the cyst wall collapses intraoperatively and achieve a GTR. In this case series, the authors suggest endoscopic cyst fenestration (ECF) with outpatient imaging, followed by mini-orbitozygomatic craniotomy via eyebrow incision (EOZ) for resection of cystic craniopharyngioma.
There were 5 patients included in this single-institution retrospective study. Of those patients, 4 received a GTR. The patient with a subtotal resection underwent craniotomy with an anterior interhemispheric approach to remove the remaining tumor. Four patients had preoperative hormone dysfunction; all patients required hormone replacement postoperatively. There were no surgical complications. No patients demonstrated recurrence on imaging at their most recent follow-up.
ECF followed with postoperative imaging can help determine how the cyst wall involutes. ECF followed by EOZ can provide more clarity on the geometry of the cyst wall and maximize the likelihood of GTR. This approach should be considered in patients with existing hormone dysfunction with the goal of GTR. https://thejns.org/doi/10.3171/CASE2624.
PMID:
42372305
Bibliographic data and abstract were imported from PubMed on 30 Jun 2026.
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