Authors
Evangelos P Solakis, Nikolaos P Tasis, Christos Kalyvopoulos, Athina Kapsokoulou, Christos Batsis
Published in
Cureus. Volume 18. Issue 5. Pages e109908. Epub May 30, 2026.
Abstract
Breast metastases from extramammary malignancies are uncommon. Among these, metastatic spread from uterine leiomyosarcoma is exceptionally rare. Uterine leiomyosarcoma is an aggressive mesenchymal neoplasm characterized by early hematogenous dissemination, most commonly to the lungs, liver, peritoneum, and bone. Breast involvement is distinctly unusual and may mimic primary breast carcinoma both clinically and radiologically. We report the case of a 76-year-old woman who presented with a painless enlarging mass in the upper outer quadrant of the left breast three months after hysterectomy with bilateral salpingo-oophorectomy for high-grade uterine leiomyosarcoma. Fine-needle aspiration suggested metastatic mesenchymal neoplasm, and wide local excision confirmed metastatic leiomyosarcoma. This case highlights the importance of considering metastatic disease in patients with a history of uterine sarcoma who develop new breast lesions.
PMID:
42375922
Bibliographic data and abstract were imported from PubMed on 30 Jun 2026.
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