Non-antibiotic management of bacterial keratitis.

Authors

Mizna Akbar, Christopher Phung, Alexis Monical, Mikhayla L Armstrong, John C Alverdy, Asim V Farooq

Published in

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society. Volume 40. Issue 2. Pages 120-129. Epub Jun 09, 2026.

Abstract

Bacterial keratitis (BK) is a common subtype of infectious keratitis, the most common cause of corneal blindness globally. While antibiotics are the mainstay of treatment for BK, numerous nonantibiotic treatments and adjuncts have emerged in recent years. These include, but are not limited to, collagen cross-linking, phototherapy, immunomodulators, and various forms of transplantation. The purpose of this work is to provide a comprehensive summary of the current literature, highlight promising areas of progress, and identify gaps and areas for further work in the management of BK. With rising resistance to antibiotics, this review echoes and emphasizes the call to study and establish alternative and adjunctive strategies for BK treatment.

PMID:
42376313
Bibliographic data and abstract were imported from PubMed on 30 Jun 2026.

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