Oncological Safety of Minimally Invasive Multivisceral Resection for cT4b Rectal Cancer: A Multicenter Comparison With Open Surgery.

Authors

Sho Nambara, Koji Ando, Tomoya Harima, Shinichiro Ikeda, Tetsuro Kawazoe, Hirofumi Hasuda, Kentaro Nonaka, Yuta Kasagi, Yasuo Tsuda, Yoshihiko Fujinaka, Tomonori Nakanoko, Ryota Nakanishi, Masahiko Sugiyama, Daisuke Yoshida, Kippei Ohgaki, Eiji Oki, Tomoharu Yoshizumi

Published in

In vivo (Athens, Greece). Volume 40. Issue 4. Pages 2237-2246.

Abstract

Minimally invasive surgery (MIS), including laparoscopic and robotic approaches, is increasingly used for rectal cancer but evidence of multivisceral resection (MVR) for cT4b disease by MIS is limited. This study compared short- and long-term outcomes between patients who underwent MIS or open MVR for advanced rectal cancer.
We retrospectively analyzed 32 patients with cT4b rectal cancer who underwent rectal resection with MVR at six institutions between 2011 and 2023 (open, n=9; MIS, n=23). Operative invasiveness, postoperative complications, and 3-year survival were evaluated.
Intraoperative blood loss was lower in the MIS group than in the open group (median: 220 vs. 2,500 ml; p<0.0001). After excluding those with stage IV disease (open, n=9; MIS, n=20), pathological outcomes and 3-year survival did not differ between groups.
MIS may reduce invasiveness without compromising oncological outcomes in selected patients with cT4b rectal cancer requiring MVR.

PMID:
42379757
Bibliographic data and abstract were imported from PubMed on 01 Jul 2026.

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