Assessing the health utility values of patients with six common cancers in China using the QLU-C10D: A cross-sectional survey.

Authors

Jiaxuan Shi, Lemin Wu, Yiyin Cao, Lijun Xu, Lei Leng, Haofei Li, Alina Sakhno, Hongjuan Yu, Weidong Huang

Published in

iScience. Volume 29. Issue 7. Pages 116334. Jul 17, 2026. Epub Jun 22, 2026.

Abstract

This study aimed to assess health utility values derived from the quality of life utility-core 10 dimensions (QLU-C10D) among 827 Chinese patients with six common cancers and to identify key factors influencing these values. Differences in QLU-C10D utility values across sociodemographic, behavioral, and clinical subgroups were analyzed using the Kruskal-Wallis H test, and key determinants were identified using median regression models. Gastric cancer patients had the highest median utility (0.802), and breast cancer patients had the lowest (0.671). Physical functioning and pain mainly influenced utility, especially in gastric and lung cancer. Economic pressure was most strongly associated with esophageal cancer, while disease stage was most strongly associated with breast cancer. This study assessed utility values in Chinese patients using the Chinese value set, offering key data for cost-utility analyses (CUA).

PMID:
42382996
Bibliographic data and abstract were imported from PubMed on 01 Jul 2026.

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