Successful treatment of pseudoepitheliomatous keratotic and micaceous balanitis with topical 5-fluorouracil.

Authors

U K Pallavi, Shivani, Sangita Singh, Rajesh Sinha, Kranti Chandan Jaykar

Published in

Indian journal of sexually transmitted diseases and AIDS. Volume 47. Issue 1. Pages 49-51. Epub Jan 30, 2026.

Abstract

Pseudoepitheliomatous keratotic and micaceous balanitis (PKMB) is a rare penile condition usually seen in elderly uncircumcised men. We report a case of PKMB in a 41-year-old circumcised male presenting with a hyperkeratotic plaque on the glans penis. Histopathology showed features of PKMB with mild cellular atypia. The patient refused surgery and was treated successfully with topical 5% 5-fluorouracil using a short-contact regimen, resulting in complete lesion clearance without recurrence. This case highlights a rare presentation and effective nonsurgical management of PKMB.

PMID:
42383129
Bibliographic data and abstract were imported from PubMed on 01 Jul 2026.

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