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Self-Poisoning With Prazosin and Its Off-Label Use in Australia, 2014-2024: Analysis of NSW Poisons Information Centre Data.

Created on 02 Jul 2026

Authors

Olivia B E Lal, Nicholas A Buckley, Rose Cairns

Published in

The Medical journal of Australia. Volume 224. Issue 7. Pages e70242.

Abstract

NSW Poisons Information Centre data identified 1030 deliberate prazosin self-poisonings over 11 years, rising from 13 to 170 per year (2014-2024). Young women predominated, likely due to expanded off-label (but accepted) psychiatric use of prazosin. Better evidence on benefits of off-label use is needed to justify increasing risks.

PMID:
42387257
Bibliographic data and abstract were imported from PubMed on 02 Jul 2026.

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