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Rhythmic Pattern of the Ovarian Development in Posthatching Japanese Quail (Coturnix coturnix japonica): Histological, Ultrastructural, and Immunohistochemical Study.

Created on 02 Jul 2026

Authors

Sara M M Eldesoky, Sahar Fadl

Published in

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. Volume 32. Issue 4. Jul 01, 2026.

Abstract

The posthatching development of the quail ovary is a well-organized procedure, involving the formation of different ovarian follicles to achieve its function of producing steroid hormones and eggs. This study was performed on 20 healthy Japanese quail chicks on the day of hatching and 10, 30, and 50 posthatching. The results show the differentiation of cortical germ cells into oocytes and somatic cells into pre-granulosa cells surrounding the oocyte, forming primordial follicles. Primary and secondary follicles develop, with possible atresia. The follicular thecal layers developed, and the interstitial stromal cells close to the follicle differentiate into thecal glands. The ovarian stroma is composed of interstitial glands, intermediate filaments, and lacunar channels. COX2 reacts with ovarian somatic cells differentiated into granulosa and interstitial stroma cells. Alpha Smooth Muscle Actin (α-SMA) is a marker of myofibroblast cells, while proliferating cell nuclear antigen (PCNA) indicates the oocyte development and growth. Caspase-3 is involved in the apoptosis of atretic follicles. These results advance our knowledge of avian reproduction by giving extensive insight into the posthatching development of the Japanese quail ovary. In conclusion, this research examines structural changes during the growth of ovaries and follicles at various age stages. Future research will broaden the molecular and genetic aspects of the developing ovary.

PMID:
42390902
Bibliographic data and abstract were imported from PubMed on 02 Jul 2026.

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