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IL-33 scripts cancer immunity.

Created on 03 Jul 2026

Authors

Marek Wagner

Published in

Trends in immunology. Jul 02, 2026. Epub Jul 02, 2026.

Abstract

Interleukin-33 (IL-33) is classically viewed as an alarmin, but in cancer, it may do more than merely initiate immunity. I propose that IL-33 scripts the trajectory of immunity through interconnected regulatory layers that influence how host responses are organized and ultimately resolved into either productive antitumor immunity or suppressive, repair-like states.

PMID:
42392913
Bibliographic data and abstract were imported from PubMed on 03 Jul 2026.

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