From Ineligible to Transplanted: Heath and Cost benefits of Treatment Optimisation of HFrEF in Dialysis Patients.

Authors

Salia Pol, Isaac Chung, Evangelina Gkalitsiou, Mark Peterzan, Tristan Williams, Lisa Anderson, Debasish Banerjee

Published in

European journal of cardiovascular nursing. Jul 04, 2026. Epub Jul 04, 2026.

Abstract

Dialysis patients with heart failure with reduced ejection fraction (HFrEF) are frequently excluded from kidney transplantation due to high perioperative risk.
We evaluated whether a multidisciplinary cardiorenal clinic could optimise guideline-directed medical therapy (GDMT), improve cardiac function, enable transplantation, and reduce healthcare costs.
Eleven dialysis patients were treated. Median LVEF improved from 30% to 47% (p < 0.01). After 29 months follow-up, 7 patients underwent transplantation and 4 remained active on the waiting list. Five-year estimated costs were £166,338 for dialysis versus £47,908 following transplantation.
HFrEF optimisation may restore transplant eligibility while substantially reducing long-term healthcare expenditure.

PMID:
42400269
Bibliographic data and abstract were imported from PubMed on 04 Jul 2026.

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