Transcription Factors in Breast Cancer Oncogenesis and Progression.

Authors

Lianna Fiore, Zhijie Li, Collin Montgomery, Audrey Coleman, Colin Kenny, Ronald J Weigel

Published in

Molecular and cellular biology. Pages 1-31. Jul 04, 2026. Epub Jul 04, 2026.

Abstract

Gene expression regulated through a set of transcription factors orchestrates the physiologic processes that drive mammary gland development, breast cancer oncogenesis, and breast cancer progression. This review highlights recent progress in our understanding of how transcriptional regulators mediate mammary gland development, mammary oncogenesis and maintenance of breast cancer stem cells, breast cancer phenotype, metastasis, and efforts to target transcription factors as a therapeutic approach in breast cancer.

PMID:
42401990
Bibliographic data and abstract were imported from PubMed on 05 Jul 2026.

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