Authors
Gaurav Singh, Abhishek Verma, Ankit Srivastava, Subash Chandra Gupta, Dalia Dasgupta Mandal
Published in
Discover nano. Volume 21. Issue 1. Jul 05, 2026. Epub Jul 05, 2026.
Abstract
A sustainable method was developed to synthesize zinc-coordinated lignin nanoparticles (LNP-Zn) from lignin derived from sugarcane bagasse, without the use of stabilizers. The direct coordination of Zn2+ within the lignin matrix creates a unique hybrid nanomaterial with several functions. At neutral pH, LNP-Zn had a mean particle size of 141.14 nm and a zeta potential of -30.41 mV, showing strong colloidal stability. BET analysis revealed a mesoporous structure with 37.16 m2/g surface area and 0.2858 cm³/g pore volume. XPS confirmed Zn+ coordination through oxygenated lignin moieties, while FTIR showed novel Zn-O functional groups having high thermal stability. XRD revealed that the LNP is amorphous, with a crystallite size of 0.42 nm. LNP-Zn demonstrated stronger antioxidant activity (IC50 21.26 ± 0.67 µg/mL), UV-shielding (SPF 23.87 ± 1.21), and efficient dye degradation. LNP-Zn showed remarkable biocompatibility (91.58 ± 2.08% viability of HEK-293 cells at 1000 mg/l) and dose-dependent cytotoxicity at high concentrations, indicating limited intrinsic anticancer activity and primarily supporting a biocompatible profile. Moreover, LNP-Zn boosted plant growth with a 189.17 ± 7.97% root enhancement in Vigna radiata (L.) R. Wilczek. Despite these promising results, further studies are needed to elucidate long-term biological safety, environmental fate, and the mechanisms underlying Zn-lignin interactions.
PMID:
42402091
Bibliographic data and abstract were imported from PubMed on 05 Jul 2026.
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