Impact of lycopene supplementation on oxidative balance, heat-shock proteins, and lipid profile in heat-stressed goat kids.

Authors

Atul Kumar Verma, Gulab Chandra, Rakesh Kumar Singh, Devesh Kumar Yadav, Prem Sagar Maurya, Ahmad Fahim, Debashis Roy, Pratibha Singh, Priyanka Rani, Mala Singh

Published in

International journal of biometeorology. Volume 70. Issue 7. Jul 05, 2026. Epub Jul 05, 2026.

Abstract

The present study was conducted to assess the effects of lycopene (LP) supplementation on antioxidant status, lipid peroxidation, heat-shock proteins, and lipid profile in heat-stressed goat kids. Twenty-one healthy growing Barbari goat kids (4-8 months old) with an average body weight of 9.87 ± 1.09 kg were randomly allocated into three experimental groups, comprising seven animals per group. The activities of superoxide dismutase, catalase, glutathione peroxidase, and total antioxidant capacity increased linearly (P < 0.023) with increasing dietary LP levels. Conversely, concentrations of myeloperoxidase, reactive oxygen species modulator-1, and thiobarbituric acid reactive substances declined linearly (P < 0.001) as LP inclusion in the diet increased. Dietary LP supplementation significantly decreased (P < 0.05) heat shock protein 70, heat shock protein 90, and cortisol concentrations, with the lowest values observed at 100 mg LP/kg DM. Total cholesterol levels were not affected by LP supplementation. However, dietary LP reduced (P < 0.05) low-density lipoprotein cholesterol and triglyceride concentrations, with the most pronounced effect at 100 mg LP/kg DM. High-density lipoprotein cholesterol concentrations were significantly increased (P < 0.05) by LP supplementation, showing the greatest response at 100 mg LP/kg DM. Overall, supplementation of LP at 50 or 100 mg/kg DM improved antioxidant status and modulated the lipid profile by reducing oxidative stress markers, with the highest beneficial response observed at 100 mg LP/kg DM.

PMID:
42402074
Bibliographic data and abstract were imported from PubMed on 05 Jul 2026.

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