Prognostic landscape of immune cell infiltration in STAD and correlation of immune-related genes and STAD prognosis.

Authors

Yang Lv, Yunhui Jiang, Jie Wu, Shenglong Guo, Guojun Du

Published in

Computer methods in biomechanics and biomedical engineering. Pages 1-11. Jul 06, 2026. Epub Jul 06, 2026.

Abstract

We aimed to investigate the potential significance of immune response in Stomach adenocarcinoma (STAD). We obtained 118 immune related DEGs, including 49 up-regulated and 69 down-regulated genes. The results showed that the high expression of CD36, GGT5 and DCN. The survival analysis found that M2 macrophages, resting mast cells and memory resting CD4 T cells were significantly related to the prognosis. IHC showed that CD36 had a higher expression level in the primary tumor, DCN was highly expressed in both tumor and paracancer tissues, however, GGT5 was not expressed in tumor tissue. CD36 may be possible targets for STAD diagnosis and treatment.

PMID:
42406644
Bibliographic data and abstract were imported from PubMed on 07 Jul 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.