Right insular glioma in right-handed patient with bilateral language dominance: a multimodal guided awake craniotomy. Illustrative case.

Authors

Diogo Moniz- Garcia, Panayiotis Pelargos, Eric C Leuthardt, A James Fessler, Matthew F Glasser, Gregory J Zipfel, Dimitrios Mathios

Published in

Journal of neurosurgery. Case lessons. Volume 12. Issue 1. Jul 06, 2026. Epub Jul 06, 2026.

Abstract

Language processing occurs overwhelmingly in the left hemisphere in right-handed patients. However, right hemispheric dominance or bilateral distribution of language can be observed with important surgical implications for lesions affecting eloquent language regions.
The authors present an illustrative case of a right-handed female patient harboring a right-sided frontal operculum tumor with right-sided language dominance in which the tumor was resected by an awake craniotomy.
The applicability of task-based and resting-state functional networks in guiding surgical decision-making in cases of atypical language localization is illustrated. https://thejns.org/doi/10.3171/CASE26131.

PMID:
42407104
Bibliographic data and abstract were imported from PubMed on 07 Jul 2026.

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