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The gut microbiota-bone marrow axis: an emerging role in chemotherapy-induced myelosuppression.

Created on 07 Jul 2026

Authors

Li Gong, Yeqi Wang, Yongsheng Li, Junli Huang

Published in

NPJ biofilms and microbiomes. Jul 06, 2026. Epub Jul 06, 2026.

Abstract

Accumulating evidence indicates that gut microbiota extensively modulates the toxicity of chemotherapeutics. However, the role of microbiota in chemotherapy-induced myelosuppression (CIM) remains poorly characterized. This review synthesizes the pivotal role of gut microbiota in regulating hematopoiesis, summarizes recent findings on the links between gut microbiota and CIM, and discusses emerging strategies for alleviating CIM through microbiota modulation. Our analysis pinpoints key gaps and novel insights for targeted CIM therapies.

PMID:
42409791
Bibliographic data and abstract were imported from PubMed on 07 Jul 2026.

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