Authors
Yifan Si, Linfei Li, Yuanzhang Jiang, Kaisong Huang, Hanshui Zhang, Zihui Zhu, Zuopan Huang, Jinlian Hu, Lumin Yang, Zhichao Dong
Published in
Materials horizons. Jul 07, 2026. Epub Jul 07, 2026.
Abstract
Dry electrospun nanofibrous facial masks (D-ENFMs) have emerged as a promising platform in nano/biomaterials research, attributed to their eco-friendly nature and convenient use. However, their practical application is significantly hindered by three critical barriers: low active ingredient loading capacity, slow dissolution kinetics, and undesirable solid residues after use. Inspired by the unique "dry-state preservation and wet-state release" survival strategy of Anastatica hierochuntica, a bioinspired core-sheath beaded-structured nanofibrous membrane (B-NFM) is developed via one-step emulsion electrospinning. This architecture enables long-term stable encapsulation of squalane emulsion droplets in the dry state and triggers ultra-fast dissolution upon contact with moisture, followed by efficient moisturization through the synergistic "water locking-hydration replenishment-barrier repair" mechanism of squalane. The surfactant coconut diethanolamide plays a dual critical role: stabilizing the oil-in-water emulsion for efficient squalane encapsulation, and modulating molecular reorganization to impart superhydrophilicity, enabling instantaneous dissolution and complete residue elimination. Notably, this one-step strategy is successfully scaled to a 256-needle roll-to-roll electrospinning system, achieving a daily output of 155.52 m2. This bioinspired design paradigm will pave the way for a new generation of sustainable, high-performance nanomaterials for advanced skincare applications.
PMID:
42411134
Bibliographic data and abstract were imported from PubMed on 07 Jul 2026.
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