Authors
Jürgen Fuchshuber, Henrik Kessler, Aram Kehyayan, Magdalena Pape, Tobias Hofmann, Matthias Rose, Katrin Imbierowicz, Franziska Geiser, Antonie Bierling, Kerstin Weidner, Jörg Rademacher, Silke Michalek, Eva Morawa, Yesim Erim, Martin Teufel, Alexander Bäuerle, Stanislav Heinzmann, Claas Lahmann, Eva Milena Johanne Peters, Johannes Kruse, Dirk von Boetticher, Christoph Herrmann-Lingen, Mariel Nöhre, Martina de Zwaan, Ulrike Dinger, Hans-Christoph Friederich, Alexander Niecke, Christian Albus, Rüdiger Zwerenz, Manfred Beutel, Casper Roenneberg, Peter Henningsen, Barbara Stein, Christiane Waller, Philipp Wülfing, Carsten Spitzer, Andreas Stengel, Stephan Zipfel, Katja Weimer, Harald Gündel, Stephan Herpertz, Stephan Doering
Published in
European journal of psychotraumatology. Volume 17. Issue 1. Pages 2677274. Epub Jul 07, 2026.
Abstract
Background: The study investigates the association between personality functioning (PF) and post-traumatic stress disorder (PTSD) symptoms in a large naturalistic clinical sample using a network analytical approach.Objectives: It aims to determine whether the previously observed link between PF and PTSD persists after controlling for frequent comorbidities (depression, anxiety and somatic symptoms), and to identify bridges connecting both clinical constructs.Methods: A regularised partial correlation network between PF, PTSD, as well as depression, anxiety and somatic symptoms was estimated at the total scale, subdomain and item level. For this aim, data from the Multicenter Effectiveness Study of Inpatient Psychosomatic Psychotherapeutic Treatment (MEPP) were reanalysed, comprising an overall N = 1899 patients (Age: M = 39.73y, SD = 14.11, range = 18-84; female = 69%).Results: A robust conditional association between PF and PTSD (E = .31) was observed. Among PF subdomains, self-perception (E = .18), and relationship model (E = .21) showed direct links to PTSD. Symptom-level analysis identified negative beliefs (PTSD) and self-esteem, interpersonal distrust and affective dysregulation (PF) as the central bridge nodes connecting both constructs.Conclusions: The relationship between personality functioning and PTSD is specific and distinct from general distress. A treatment focus on negative self-perception, interpersonal (dis)trust and affective regulation might be a promising pathway for symptom reduction, specifically in patients with comorbid PTSD and PF impairments.Trial registration: German Clinical Trials Register identifier: DRKS00016412..
PMID:
42411276
Bibliographic data and abstract were imported from PubMed on 07 Jul 2026.
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