Azo compounds as key intermediates in the synthesis of cinnolines. Recent advances.

Authors

Xabier Jiménez-Aberásturi, Xabier Del Corte, Jesús M de Los Santos, Javier Vicario

Published in

Organic & biomolecular chemistry. Jul 07, 2026. Epub Jul 07, 2026.

Abstract

Over the past decades, azo compounds have emerged as versatile and efficient building blocks for the construction of cinnoline frameworks due to their ready availability, structural diversity, and unique reactivity profiles. This review provides a comprehensive overview of recent advances in the use of azo compounds for cinnoline synthesis, highlighting transition-metal-catalyzed C-H activation modern strategies, cycloaddition reactions and classical methods (von-Richter, Widman-Stoermer or Borsche-Herbert).

PMID:
42411988
Bibliographic data and abstract were imported from PubMed on 07 Jul 2026.

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