The EBV timing hypothesis: How the age of primary infection may explain global variation in multiple sclerosis.

Authors

Laura R Naydovich, Joseph R Berger

Published in

Multiple sclerosis and related disorders. Volume 113. Pages 107374. Jul 04, 2026. Epub Jul 04, 2026.

Abstract

The age of acquisition of EBV infection has been suggested to be determinative in whether an individual develops multiple sclerosis. This correlation may be the consequence of the difference in the immune response to EBV between children and adults. In this narrative review, we explored whether the age of EBV infection as determined by seroepidemiological studies is associated with the prevalence of MS in various populations.

PMID:
42418890
Bibliographic data and abstract were imported from PubMed on 09 Jul 2026.

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