Authors
Eva Verónica Deschutter, Alejandra Bontcheff, Verónica Higa, Marianela Borra, Alejandra Gaiano, María Florencia Cechetto, Elcira Olmedo, Horacio Zelaya, Claudia Mercado, Miriam Calvari, Martin Brizuela
Published in
American journal of perinatology. Jul 08, 2026. Epub Jul 08, 2026.
Abstract
i.
To describe clinical, laboratory, and follow-up characteristics of neonates with confirmed dengue infection. ii.
Observational, descriptive, retrospective, and multicenter study including neonates with confirmed congenital dengue hospitalized at 6 centers from Argentina, between July 2023 and July 2024. Confirmation required virological or serological testing in both mother and neonate. Data were collected anonymously via REDCap and analyzed with RStudio. iii.
58 neonates were included. Most pregnant individuals presented with fever, myalgia, and headache. Maternal diagnosis was confirmed mainly by NS1 antigen (59%) and PCR (43%); 9% were serotyped, with 4/5 serotypes corresponding to DENV1. Fifty-two pregnant individuals were hospitalized. Median gestational age at birth was 38 weeks; and 21% of neonates were preterm. Most deliveries were cesarean. At admission, 74% of neonates were asymptomatic; 26% showed respiratory distress or temperature instability. Diagnosis was confirmed by PCR in 59% of neonates. Two preterm neonates required mechanical ventilation. Median hospital stay was 9 days. 57% of neonates developed thrombocytopenia within the first week of life. No deaths or sequelae were recorded in neonates. One mother died because of severe dengue with shock. iv.
In this multicenter registry, 74% of neonates were asymptomatic and 21% preterm, with no deaths or sequelae at discharge and 30 days of follow-up.
PMID:
42419708
Bibliographic data and abstract were imported from PubMed on 09 Jul 2026.
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