[Role of Thalamocortical Circuits in Action Decision-Making].

Authors

Masanori Matsuzaki

Published in

Brain and nerve = Shinkei kenkyu no shinpo. Volume 78. Issue 7. Pages 769-773.

Abstract

Animals constantly decide whether to act or remain inactive. In mice, motor thalamus inputs to the secondary motor cortex (M2) are crucial for this process. The motor thalamus represents the relative action value, irrespective of whether the animal acts, and is transmitted to M2 before action initiation. Furthermore, this value signal is transformed into M2 activity associated with motor initiation, leading to action execution. This study elucidates the circuit mechanism through which values are transformed into actions.

PMID:
42419758
Bibliographic data and abstract were imported from PubMed on 09 Jul 2026.

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