Authors
Adanze Nge Cynthia
Published in
Journal of epidemiology and global health. Jul 09, 2026. Epub Jul 09, 2026.
Abstract
Disease elimination, as defined by the World Health Organization (WHO), denotes the sustained reduction of pathogen transmission to zero within a defined geographic area through ongoing public health intervention. In practice, however, certification of elimination status has frequently operated as a terminal designation, reshaping funding and signalling that a problem has been resolved. This perspective argues that such a conception is both scientifically untenable and operationally hazardous. Drawing on three concurrent, well-documented resurgences, measles across the Americas and Europe, circulating vaccine-derived poliovirus (cVDPV) in high-income settings, and accelerating global cholera mortality, this paper identifies three mechanistically distinct but institutionally convergent pathways through which disease control gains erode: immunological erosion driven by unvaccinated birth-cohort accumulation, virological re-emergence via vaccine-derived pathogen variants in under-immunised populations, and structural collapse of water, sanitation, and hygiene (WASH) infrastructure in conflict-affected settings. Across all three, a shared governance failure is evident: post-certification frameworks reward achievement rather than mandate sustained maintenance. Four targeted reforms are proposed, pathway-sensitive post-certification monitoring, quantitative threshold-triggered status reviews, integration of structural resilience metrics, and reform of public-facing elimination communication. Disease elimination is better understood as a condition of managed equilibrium than as a milestone: it is not secured by certification, it is continuously earned.
PMID:
42423845
Bibliographic data and abstract were imported from PubMed on 09 Jul 2026.
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