Authors
Naif M Alraihan, Maddy French, Danielle Collingridge Moore, Luigi Sedda
Published in
PLOS digital health. Volume 5. Issue 7. Pages e0001495. Epub Jul 09, 2026.
Abstract
Public health informatics (PHI) tools, including Geographic Information Systems (GIS), Electronic Health Records (EHRs), and Health Information Exchange systems, are increasingly applied to dengue fever surveillance, prevention, and control. Despite their growing adoption, a synthesis of empirical evidence examining their real-world application across endemic settings has not previously been conducted. This systematic review aimed to examine how PHI tools have been applied to dengue risk management, and to evaluate the certainty of evidence supporting their use. A structured literature search was conducted across PubMed, EBSCO/MEDLINE, and Web of Science. Nineteen peer-reviewed empirical studies published between 2010 and 2024 were included following eligibility screening against pre-defined inclusion and exclusion criteria. Study quality was assessed using the Newcastle-Ottawa Scale adapted for cross-sectional studies. Certainty of evidence was evaluated using the GRADE framework across five domains: risk of bias, inconsistency, indirectness, imprecision, and publication bias. Findings were synthesised narratively and organised into three functional categories: mapping and visualisation (n = 12), epidemiological insights (n = 5), and enhanced surveillance (n = 2). GIS was the most frequently used tool, consistently identifying dengue hotspots and supporting spatial dengue risk mapping across diverse geographic settings. EHR-linked health information systems supported epidemiological profiling and, in a limited number of studies, improved outbreak detection. Certainty of evidence was rated as very low across all three categories, reflecting the low evidence associated to observational study designs, methodological heterogeneity, and the uniform reporting of positive findings across all included studies. PHI tools show consistent descriptive utility in dengue surveillance across diverse settings. However, given the very low certainty of evidence, conclusions should be interpreted with caution. Gaps remain in high-burden regions including Sub-Saharan Africa and the Middle East. Standardised evaluation frameworks, broader geographic representation, and integration with emerging digital health technologies are needed to strengthen the evidence base. Systematic review registration: PROSPERO; registration number CRD42024572021.
PMID:
42424242
Bibliographic data and abstract were imported from PubMed on 10 Jul 2026.
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