Coronary heart disease and chronic obstructive pulmonary disease prevalence and temporal trends among United States adults: a national population-based study.

Authors

Muinat Abolore Idris, Valerie M Valenzuela, Juan Aguilera

Published in

Frontiers in epidemiology. Volume 6. Pages 1840095. Epub Jun 25, 2026.

Abstract

Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) are two independent leading causes of morbidity and death, with co-existence contributing substantially to morbidity and deaths among aging populations. Despite growing evidence on the impact of COPD-CVD co-existence, little is known about COPD-CHD co-morbidity, as other previous studies mostly examine CVD as a single aggregated health outcome, obscuring disease-specific trajectories.
To assess 5-year national trends and sociodemographic disparities in the prevalence of coexisting CHD-COPD co-morbidity.
Using the 2020-2024 National Health Interview Survey Integrated Public Use Microdata Series adults' dataset, we estimated the national prevalence of CHD-COPD co-morbidity. Weighted descriptive statistics, multivariate regression models, and sensitivity analysis were used to examine the associations.
CHD-COPD co-morbidity prevalence showed no statistically significant increase from 2020 to 2024; although the estimated linear trend was positive, it did not reach statistical significance (OR per 1-year increase = 1.04; 95% CI: 0.997-1.08; p = 0.072). Age, sex, body mass index, race/ethnicity, geographical region, smoking status, insurance status, income, and educational attainment were strong independent predictors of CHD-COPD co-morbidity. Older age (aOR: 1.004; 95% CI: 1.003-1.004, p < 0.0001) was independently associated with higher odds; current and former smokers had approximately 5-6 times higher odds of CHD-COPD co-morbidity.
CHD-COPD co-morbidity is a rare but clinically significant condition, with a stable adjusted prevalence of approximately 0.35%-0.43% annually among United States adults from 2020 to 2024. Smoking, older age, male sex, lower income, and Southern residence were the strongest independent predictors of CHD-COPD co-morbidity. These findings underscore the need for integrated, sociodemographically targeted prevention and chronic-disease management strategies addressing shared cardiopulmonary risk factors, particularly tobacco use, across vulnerable populations.

PMID:
42428747
Bibliographic data and abstract were imported from PubMed on 10 Jul 2026.

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