Preoperative Systemic Coagulation Inflammation Index may be a Predictor of Worse Outcomes After Carotid Endarterectomy.

Authors

Mesut Engin, Orhan Guvenc, Ahmet Kagan As, Ufuk Aydin, Yusuf Ata, Senol Yavuz

Published in

Sisli Etfal Hastanesi tip bulteni. Volume 60. Issue 2. Pages 180-187. Epub Jun 29, 2026.

Abstract

Stroke is a significant disease associated with high mortality and morbidity rates, and carotid artery stenosis (CAS) is one of its most important causes. Although endovascular applications have increased in the treatment of CAS, carotid endarterectomy (CEA) surgery remains prominent. The systemic coagulation inflammation index (SCII) has emerged as an important marker indicating coagulation and inflammatory status. In this study, we aimed to investigate the effect of SCII values on worse outcomes during 30-day follow-up in patients who underwent CEA.
This retrospective study consecutively included patients who underwent carotid endarterectomy at our clinic between January 1, 2020, and June 1, 2025. Patients who did not develop worse outcomes within the first 30 days after surgery were assigned to Group 1, and those who did were assigned to Group 2. Worse outcomes in the study were defined as stroke, myocardial infarction, and death.
A total of 594 patients underwent elective CEA surgery. The 546 patients in Group 1 and the 48 patients in Group 2 had median ages of 71 (44-88) and 69 (41-91) years, respectively (p=0.185). As a result of the multivariate analysis, the presence of coronary artery disease (OR: 1.690, 95% CI: 1.210-1.984, p=0.032) and high SCII values (OR: 1.780, 95% CI: 1.270-2.894, p<0.001) were determined as independent predictors of worse outcomes after CEA surgery.
Our results indicated that high SCII values were associated with worse outcomes within 30 days after CEA. In patients undergoing CEA, SCII values can be calculated preoperatively to identify at-risk patient groups; therefore, measures can be taken for patient management and follow-up in the postoperative period.

PMID:
42428720
Bibliographic data and abstract were imported from PubMed on 10 Jul 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.