Authors
Cole Wymore, Eliezer Santos León, Priyanka Vakkalanka, Uche Okoro, Karisa K Harland, Brian M Fuller, Kalyn Campbell, Morgan B Swanson, Brett Faine, Anne Zepeski, Edith A Parker, Luke J Mack, Amanda Bell, Katie DeJong, Keith Mueller, Elizabeth Chrischilles, Christopher R Carpenter, Kelli Wallace, Michael P Jones, Marcia M Ward, Nicholas M Mohr
Published in
PloS one. Volume 21. Issue 7. Pages e0351133. Epub Jul 10, 2026.
Abstract
The objective of this study was to assess whether interhospital transfer delays completion of the Surviving Sepsis Campaign (SSC) 3-hour bundle among rural sepsis patients.
We conducted a multicenter (n = 23) cohort study among adult rural sepsis patients in an ED-based telemedicine network between August 2016 and June 2019. The primary exposure was interhospital transfer and the primary outcome was completion of the SSC 3-hour bundle. Secondary outcomes included SSC component adherence, ED length-of-stay, and in-hospital mortality. We used a Cox proportional hazards model to evaluate time to bundle completion by transfer status, generalized linear models for dichotomous outcomes, and linear and quantile regression for ED length-of-stay.
A total of 1,191 patients were treated in participating hospitals, with 359 (30%) undergoing interhospital transfer. SSC bundle adherence was similar in both groups (difference 2.2%; 95% confidence interval [CI]: - 2.2, 6.5%). Among eligible patients, transfer was associated with a longer ED length-of-stay (3.1 hours vs 2.6 hours; difference 0.6 hours; 95%CI: 0.4, 0.7).
PMID:
42430347
Bibliographic data and abstract were imported from PubMed on 11 Jul 2026.
Read full publication at:
Please sign in
to see all details.
Advertisement
Stats
- Recommendations n/a n/a positive of 0 vote(s)
- Views 6
- Comments 0