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Transient New-Onset Atrial Fibrillation During Acute Chest Pain Unmasking Severe Multivessel and Left Main Coronary Artery Disease: A Case Report.

Created on 12 Jul 2026

Authors

Abdulmohsen H Al Mefarrej, Amjaad Almarjan, Fayez A Al Zubair

Published in

Cureus. Volume 18. Issue 6. Pages e110656. Epub Jun 11, 2026.

Abstract

We report a case involving a rare finding observed during a medical evaluation in a patient who visited the emergency department due to acute cardiac chest pain. The patient presented with transient atrial fibrillation (AF) during examination at the emergency department, which was a warning sign observed in this patient, implicating a significant ischemic change on electrocardiography during chest pain. This case showed how the patient was evaluated and treated in accordance with new ischemic changes detected during a transient episode of AF, despite the initial absence of high troponin levels and almost normal electrocardiography findings during sinus activity. Notably, AF during acute chest pain is rarely reported in the literature. The presence of AF might be a clinical marker of major coronary artery disease in symptomatic patients. The current case report was supported by coronary artery angiography findings. The patient received full revascularization treatment, and he was eventually discharged home without recurrence of AF during follow-up. AF played a major diagnostic role in the identification of the patient's condition.

PMID:
42437213
Bibliographic data and abstract were imported from PubMed on 12 Jul 2026.

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