High-Grade Serous Carcinoma of the Ovary: A Case Report.

Authors

Farah Jiandani, Savita Somalwar, Anuja Bhalerao

Published in

Cureus. Volume 18. Issue 6. Pages e110751. Epub Jun 12, 2026.

Abstract

Ovarian cancer (OC) is one of the most common gynecological cancers, representing the abnormal and uncontrolled growth of ovarian cells leading to the formation of tumors. It is one of the leading causes of death in the majority of nations. A wide range of factors, such as lifestyle, environmental factors, genetic factors, hormonal changes, and repeated miscarriages, influence the emergence of OC. Contrary to these factors, breastfeeding, pregnancy, oral contraceptive pills (OCP), and tubal ligation lower the risk of getting OC. The classification of OC as early-stage, advanced-stage, low-grade, or high-grade cancer mainly depends on the histological subtype present at the time of detection. There are various classification systems used to classify OC, but the two most commonly used ones are the International Federation of Gynaecology and Obstetrics (FIGO) staging system and the tumor-node-metastasis (TNM) staging system. The present case is of a 63-year-old female patient diagnosed with high-grade serous carcinoma of the ovary with a TNM staging grade of T_1a N₀ M₀ and an FIGO A1 grade, managed effectively with staging laparotomy. The case study concludes that early identification and care of OC can prevent disease progression, resulting in a better quality of life and prolonging the patient's life. It is crucial to conduct frequent evaluations of a specific age group in the older population to avoid such occurrences.

PMID:
42438662
Bibliographic data and abstract were imported from PubMed on 13 Jul 2026.

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