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Molecularly imprinted polymer-based fluorescent sensors for rapid and specific detection of target pesticides.

Created on 13 Jul 2026

Authors

Haoqi Jia, Rui Li, Xiaoxiao Hong, Xin Dong, Shengxue Ye, Weiwei Li, Jianlin Li, Fenying Wang, Qianjin Li

Published in

Analytical methods : advancing methods and applications. Jul 13, 2026. Epub Jul 13, 2026.

Abstract

This study presents a novel fluorescence sensing platform based on molecularly imprinted polymers (MIPs) for the detection of imidacloprid and chlorpyrifos, two widely used pesticides with potential food safety risks. The fluorescent MIPs (FMIPs) were synthesized via a sol-gel polymerization method using 3-aminopropyltriethoxysilane (APTES) as the functional monomer, and fluorescein isocyanate coupled APTES as the fluorescent functional monomer. The resulting FMIPs exhibited high specificity and strong fluorescence quenching responses upon binding to the target pesticides. Under optimized conditions, the corresponding FMIP sensors displayed a linear detection range of 0.02-2 µM for imidacloprid and 0.04-10 µM for chlorpyrifos, with detection limits of 0.012 µM and 0.037 µM, respectively. In addition, the FMIP sensors could realize the specific recognition of the target pesticides within 10 minutes. Validation using water samples achieved spiked recoveries of 75.6-106.5% with relative standard deviations below 9.3%, confirming its practicality for application in real samples.

PMID:
42439014
Bibliographic data and abstract were imported from PubMed on 13 Jul 2026.

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