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Synergistic Effect of Adding Calcium Hydroxide and a Quaternary Ammonium Compound on the Degradation of Coccidia Oocysts by an Ortho-phenylphenol-Based Disinfectant.

Created on 13 Jul 2026

Authors

Kazuaki Takehara, Shotaro Maehana, Hiroki Izawa, Makoto Kubo, Shunsuke Yamaguchi, Hiroki Matsumoto

Published in

Avian diseases. Volume 70. Issue 2. Pages 214-218.

Abstract

Only a limited number of disinfectants are capable of inactivating coccidia oocysts, and in Japan, ortho-phenylphenol-based disinfectants (a combination of cresol and 1,2-dichlorobenzene) are mainly used. However, resistance of oocysts to ortho disinfectants has been reported. Previously, we demonstrated a synergistic enhancement of microbicidal activity by adding food-additive-grade calcium hydroxide with a mean particle size of 10 µm to a quaternary ammonium compound. In the present study, we found that the addition of calcium hydroxide and a quaternary ammonium compound to the ortho disinfectant synergistically and significantly enhanced its oocysticidal effect.

PMID:
42440288
Bibliographic data and abstract were imported from PubMed on 13 Jul 2026.

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