Authors
Silvan Wittenberg, Anne Flörcken, Franziska Borchert, Pirus Ghadjar, Annika Strönisch, Tomasz Dziodzio, Frederik Maximilian Schäfer, Sanas Mirhoseiny, Armin Jarosch, Daniel Rau
Published in
Orthopadie (Heidelberg, Germany). Jul 13, 2026. Epub Jul 13, 2026.
Abstract
Soft tissue sarcomas are rare, heterogeneous mesenchymal malignancies with variable prognosis. Management requires structured diagnostics and interdisciplinary treatment at specialized centers. Imaging with MRI or CT and a carefully planned biopsy are essential for diagnosis and surgical strategy. In curative settings, complete R0 resection is the primary goal, while metastatic disease requires an individualized approach. Low-grade sarcomas are often treated with marginal resection, whereas high-grade tumors require multimodal therapy including neoadjuvant treatment, wide resection, and adjuvant radiotherapy. Surgical margins depend mainly on anatomical barriers. Functional outcomes and reconstruction are key considerations. Limb preservation is usually achievable, while amputation is rarely necessary.
PMID:
42439936
Bibliographic data and abstract were imported from PubMed on 13 Jul 2026.
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