[In utero treatment of congenital diaphragmatic hernia].

Authors

Alexandra Benachi, Alexandra Letourneau, Julien Saada

Published in

La Revue du praticien. Volume 76. Issue 6. Pages 646-649.

Abstract

Congenital diaphragmatic hernia is a rare malformation with a prevalence of approximately 1 in 3,000 births. Pulmonary development during fetal life is variably impaired, and newborns typically present pulmonary hypoplasia, often associated with pulmonary hypertension. In France, in 2008, the creation of the Rare Diseases Reference Center (CRMR) for Congenital Diaphragmatic Hernia, affiliated with the Rare Disease Network FIMATHO (Program for Rare Abdominothoracic Diseases), enabled the establishment of a territorial network ensuring relatively homogeneous expertise across the country. After more than 10 years of evaluation and two international randomized trials, in utero surgery by fetal tracheal occlusion has become one of the therapeutic options for fetuses with severe and moderate forms of congenital diaphragmatic hernia.

PMID:
42439141
Bibliographic data and abstract were imported from PubMed on 13 Jul 2026.

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