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A Cannula-Based Sequential Injection Protocol for Non-surgical Rhinoplasty in East Asian Patients.

Created on 14 Jul 2026

Authors

Jiandong Ye, Xiancheng Wang, Kemin Yi, Pei Zou, Hao Liu

Published in

Aesthetic plastic surgery. Jul 13, 2026. Epub Jul 13, 2026.

Abstract

Non‑surgical rhinoplasty is increasingly popular for nasal augmentation in East Asian patients. However, a standardized, anatomy‑driven protocol for the sequential and layered correction of the nasal tip, dorsum, and glabellar complex-key aesthetic units in the Asian nose-is still lacking.
In this dual‑center retrospective study, 528 East Asian patients (490 females, 38 males; mean age 27.7 years) underwent non‑surgical rhinoplasty between 2020 and 2024. A high‑G' hyaluronic acid filler was injected via cannula in a predefined sequence: first, the nasal tip via fibrous septal deposition; followed by the dorsum and glabellar triangle. Outcomes were assessed using ·FACE‑Q and 3D facial scanning (MVS‑N1) preoperatively and at 9 months.
Three‑dimensional analysis of the 426 patients who received the full three-site protocol showed significant improvements from baseline in nasal length (+ 2.62 mm), tip projection (+ 3.69 mm), nasolabial angle (+ 5.7°), and nasofrontal angle (- 9.4°) (all p < 0.001). FACE‑Q scores significantly improved across all 528 patients in satisfaction (+ 44.4 points), social function (+ 26.2), psychological well‑being (+ 28.1), and reduced distress (- 39.4) (all p < 0.001). No vascular complications occurred; 11 cases had transient erythema that resolved spontaneously or with conservative measures.
The sequential "tip‑dorsum‑glabella" injection protocol, featuring a refined cannula‑based technique for fibrous septal tip augmentation, was associated with a low complication rate and significant short‑term improvements in patient‑reported and anthropometric outcomes in this retrospective analysis, suggesting that it is a clinically feasible approach for non‑surgical rhinoplasty in East Asian patients.
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

PMID:
42443422
Bibliographic data and abstract were imported from PubMed on 14 Jul 2026.

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