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Precision therapeutics for wound healing: Molecular targets, signalling networks, and advanced drug design strategies.

Created on 15 Jul 2026

Authors

Sibiya Ashokkumar, Rishi Ganesh Sonniyan Kumar, Esakkimuthu Shanmugasundaram

Published in

Advances in protein chemistry and structural biology. Volume 153. Pages 437-454. Epub May 09, 2026.

Abstract

The therapeutic manipulation concerning towards wound healing meets the different macroscopic levels such as immunological mechanisms, molecular signalling networks, developmental biology (regeneration) and drug discovery. From the epidermal skin infection to the deprived wound conditions, they are turned around into either scar or regenerated tissues. The restoration of tissue networks meets an intrinsic and dynamic rewinding processes from gene signals to several enzymes secretion led healing actions. Several advancements made in the wound healing materials and therapeutic assistive kits. Nanoparticle got high significant potential does not allow the drug waste rather it enhance target specific modifiers that either increase or decrease inflammatory response depend on the acute and chronic condition. And, there intrinsic pathways and growth regulators where activated in the entire process of wound healing. This review, encompasses from the rudimentary process to mechanism of highly advanced.

PMID:
42448415
Bibliographic data and abstract were imported from PubMed on 15 Jul 2026.

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