[Pleural Well-differentiated Papillary Mesothelial Tumor Presenting with 
Recurrent Pneumothorax and Pleural Effusion: A Case Report].

Authors

Zhe Li, Fanyi Kong, Bo Yang, Tianrun Song, Shuai Zhao, Xiang Song

Published in

Zhongguo fei ai za zhi = Chinese journal of lung cancer. Volume 29. Issue 5. Pages 390-394. May 20, 2026.

Abstract

Well-differentiated papillary mesothelial tumor (WDPMT) is a rare neoplasm characterized by a distinct papillary architecture, bland cytological features, and a propensity for superficial spread without stromal invasion. We herein report the diagnosis and management of a patient with pleural WDPMT presenting predominantly with recurrent spontaneous pneumothorax and pleural effusion, along with a review of the current literature on this entity. The patient was a 58-year-old female who presented with a two-week history of chest tightness and dyspnea on a background of recurrent spontaneous pneumothorax and pleural effusion over the preceding seven years. She had experienced four episodes of recurrence during that period and denied any history of asbestos exposure. Thoracoscopic exploration revealed pulmonary bullae, pleural effusion and pneumothorax, pleural thickening, and scattered grayish-white nodules on both the visceral and parietal pleura. Histopathological examination of the pleural nodule biopsy confirmed the diagnosis of WDPMT. Based on the features of this case and a review of the literature, clinicians should be aware that WDPMT may present with the atypical manifestation of recurrent spontaneous pneumothorax accompanied by pleural effusion.
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PMID:
42452868
Bibliographic data and abstract were imported from PubMed on 15 Jul 2026.

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