Treatment of Chronic Postamputation Pain With High-Frequency Bioelectric Nerve Block Over 12 Years: A Case Report.

Authors

Amol Soin, Erin Barker, Nemath Syed Shah, Nicholas J Hargus

Published in

Pain medicine case reports. Volume 10. Issue 4. Pages 353-359.

Abstract

Targeted application of high-frequency alternating current to induce reversible electrical nerve block (high-frequency nerve block [HFNB]) was recently approved for the treatment of chronic, intractable postamputation pain. Our case describes the use of HFNB for over 12 years.
In 2012, a 55-year-old woman with above-the-knee lower-limb amputation reporting episodic residual limb pain for 19 years enrolled in a pilot study of HFNB for chronic postamputation pain. During the study, the external waveform generator was replaced with a permanent implantable pulse generator, and the patient continues to use the device today. Data collected regularly at follow-up visits demonstrate sustained improvements in pain and functional outcomes and provide a long-term profile of HFNB treatment.
Our case describes long-term benefit of HFNB for chronic postamputation pain and provides detail regarding this novel therapy that cannot be derived from large studies evaluating effectiveness on a population level.

PMID:
42456073
Bibliographic data and abstract were imported from PubMed on 16 Jul 2026.

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