Authors
Neetu Vijay, Sumit Dutt Bhardwaj, Varsha Potdar, Rizwan Abdulkader Suliankatchi, Labanya Mukhopadhyay, Ramasamy Sabarinathan, Tapan Majumdar, Debasis Biswas, Rahul Narang, Manohar Lal Choudhary, Aashish Choudhary, Megha Brijwal, Ravisekhar Gadepalli, Sayantan Banerjee, Sumit Rai, Meena Mishra, Anudita Bhargava, Sanjay Singh Negi, Neeta Khandelwal, Shantala Gowdara Basawarajappa, Tanusri Biswas, N Barathi Santose, Reena Ray Ghosh, Anuradha Sood, Vaibhav Misra, K Indira, Ajanta Sharma, Vivek Gupta, Varun Goel, Joana Mary Magdaline, Umesh Varshney, T K Raji, Rupinder Bakshi, Sundararajan Thangavel, Summaiya Mullan, Girija Kannan, Pushpa Kizhakkekarammel, Kalpana George, Maria Jose Wiseman Pinto, Manjusree Shanmugham, P M Anitha, Jyoti Iravane, Lingam Jayalakshmi, AnuKumar Balakrishnan, S Siba, Agniva Majumdar, Pushpendra Singh, Gaurav Dwivedi, Raja Ray, Rahul Dhodapkar, R K Manojkumar Singh, Prerna Aggarwal, Nayana Ingole, Mahesh Kumar, Shruti Radera, Kaveri Krishnasamy, Avula Renuka Devi, Debashish Samal, Chandrasegaran Sugumari, Nandita Pal, Manish Purohit, Ranadeep Ghosh, Asis Manna, Amurtha Kumari Bodigutlapalli, Arunabha Sarkar, Wihiwot Valarie Lyngdoh, Madhulika Mistry, Mini Pritam Singh, Biswa Borkakoty, Bipasa Chakraborty, Jyoti Turuk, Ganesh Sahoo, Bashir Fomda, Bharti Malhotra, Anjli Gupta, Shrijana Gurung, Usha Kalawat, Mika Umpo, Rajesh Kumar Verma, Swagnik Roy, Respiratory virus surveillance Team@, Amita Jain, Santasabuj Das, Lalit Dar, Nivedita Gupta
Published in
BMC infectious diseases. Jul 15, 2026. Epub Jul 15, 2026.
Abstract
In December 2024 and early January 2025, China reported increased acute respiratory infections with increased detections of seasonal influenza, rhinovirus, RSV and hMPV during the Northern Hemisphere winter. We strengthened hMPV surveillance through the existing pan-India surveillance network for acute respiratory illness (ARI) and severe acute respiratory infection (SARI).
To rapidly generate nationwide situational data without overburdening laboratories already performing routine respiratory virus surveillance, each site was asked to test up to five eligible SARI samples per week for hMPV from January to April 2025. Eligible samples were hospitalized SARI cases that were negative for influenza, SARS-CoV-2 and/or RSV, as applicable to age-based testing algorithms, across 70 laboratories.
Of 8,246 enrolled SARI cases, 4,149 eligible samples were tested for hMPV under the capped weekly sampling strategy, and 59 were positive (1.42%; 95% CI: 1.10-1.83). Positivity ranged from 0.5% to 2.9% across age groups and was highest in children aged <2 years. Most patients (63%) were aged <2 years. Positivity was higher among males (1.7% vs 1.1% in females), and was highest in January (2.1%) before declining to 0.5% in April. The most common symptoms were cough (95%), fever (88%), and breathlessness (58%). Outcomes were available for 54/59 patients: 11 required ICU admission, 51 were discharged alive, and 3 died. Among seven patients with comorbidities, all were discharged alive. More than half of the sequenced viruses belonged to clade B1, followed by B2 and A2b2.
In this limited sentinel surveillance of severe respiratory infections, hMPV was detected infrequently but was observed predominantly among young children. Continued multi-season surveillance is needed to better define age-specific burden, temporal patterns, and circulating genotypes in India.
Not applicable.
PMID:
42458342
Bibliographic data and abstract were imported from PubMed on 16 Jul 2026.
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