Authors
Rajni Parmar, Vijay Yadav, Ankur Agarwal
Published in
Cureus. Volume 18. Issue 6. Pages e110845. Epub Jun 14, 2026.
Abstract
Angiosarcomas are rare sarcomas with a poor prognosis, and treatment modalities are still being established. Cutaneous and soft tissue angiosarcomas are frequently reported; however, those occurring at rare sites have fewer published case reports and series. An unusual case was encountered at our institute: a 25-year-old woman with an ovarian tumor in which angiosarcoma was diagnosed in a background of teratoma. The details of surgery, gross appearance, histopathological findings, and immunohistochemistry (IHC) workup leading to the diagnosis are presented, along with a review of the current literature. The ease of reaching the histological diagnosis of angiosarcoma depends on the site of occurrence and degree of differentiation. Recent advances in therapeutics, along with emerging evidence from clinical trials, have demonstrated promising outcomes in the treatment of angiosarcoma. It is possible to reach an accurate diagnosis by keeping in mind its histological variability and key histologic features and by performing an appropriate IHC workup. Improving treatment results for patients with angiosarcoma involves a shift toward multimodal therapy and precision medicine, and recent breakthroughs offer hope for better outcomes.
PMID:
42460230
Bibliographic data and abstract were imported from PubMed on 16 Jul 2026.
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