Authors
Julian Bucur, Zoha Mian, Max Liu, Blake Anderson, Jakob Wend, Klemens Paul Kaiser, Ethan Drifill, Liliana Werner, Thomas Kohnen
Published in
Journal of cataract and refractive surgery. Jul 15, 2026. Epub Jul 15, 2026.
Abstract
To analyze intraocular lenses (IOL) explanted at a single center between December 2012 and March 2025 with regard to explantation indications, patient demographics and light microscopic findings.
Goethe University Frankfurt, and John A. Moran Eye Center, University of Utah.
Retrospective laboratory study.
Explanted IOLs were catalogued according to patient demographics, intraocular duration, explantation indication and light microscopic appearance. When required, histochemical and histological staining was performed to further characterize observed deposits.
One hundred and fifty-one IOLs from 151 patients were examined. 87 of the patients were male (58%), 64 were female (42%). The mean patient age at explantation was 70.9 years ± 16.2 (standard deviation, SD), the mean intraocular duration was 10.5 years ± 8.1. Single-piece IOLs showed a predisposition to pigmentary dispersion, hydrophobic acrylic IOLs to glistenings and hydrophilic acrylic IOLs to calcification. Silicone IOLs demonstrated the highest rate of Soemmering's ring (SR) traces within their capsular bag, although only in less advanced stages.
The findings largely confirm the known material-specific susceptibility of IOLs to characteristic microscopic changes. Owing to its long observation period, this study reflects temporal changes in IOL material selection, model usage, and explantation indications over the past decades.
PMID:
42460456
Bibliographic data and abstract were imported from PubMed on 16 Jul 2026.
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