Authors
Mati Ullah, Muhammad Rizwan, Muhammad Ihtesham Waheed, Muhammad Shoaib Alam, Sami Ullah Jan, Ali Raza, Muhammad Faisal Shahid, Vivian Andoh, Yong Chen
Published in
World journal of microbiology & biotechnology. Volume 42. Issue 8. Jul 17, 2026. Epub Jul 17, 2026.
Abstract
Probiotics have long been recognized for their broad interests in regulating the immune system and promoting gut health. Recently, they have become a key component in the growing field of precision medicine. This review thoroughly examines the transition of probiotics from general health enhancers to advanced, targeted therapies designed to address the unique characteristics of different microbiomes, genetic profiles, and individual health statuses. It emphasizes various mechanisms by which probiotics affect host physiology, including the regulation of immune responses, the modulation of metabolism, and the promotion of intestinal interactions. This review further explores the integration of psychobiology, next-generation probiotics (NGP), modified strains, artificial intelligence, and synthetic biology technologies to develop personalized probiotic therapies. By integrating recent advances with cutting-edge technologies, this review redefines probiotics as a crucial tool in personalized medicine, highlighting the need for innovation and collaboration to maximize their therapeutic potential.
PMID:
42463603
Bibliographic data and abstract were imported from PubMed on 17 Jul 2026.
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