[Application of cytokine-rich autologous serum in chronic Achilles tendinopathy: A case series of 3 patients].

Authors

R Vilas Boas, E Díaz Recarey, M Alonso, J Formigo-Couceiro

Published in

Rehabilitacion. Pages 101002. Jul 17, 2026. Epub Jul 17, 2026.

Abstract

This series describes 3 cases of persistent chronic Achilles tendinopathy treated with an ultrasound-guided injection of autologous cytokine-rich serum obtained using Qrem Cytokine. The patients, who were unresponsive to conservative treatments such as eccentric exercise, physiotherapy, and shockwave therapy, were tracked using the VAS, VISA-A, Roles-Maudsley, and ultrasound up to 12 months. All patients showed clear clinical improvement: pain decreased significantly (2 cases achieving a VAS score of 0 one year after treatment), and the VISA-A score increased by more than 16 points in all cases, one case achieving a score of 97/100. Ultrasound imaging revealed a moderate reduction in tendon thickness, which was more pronounced in one patient. The final Roles-Maudsley score was good or excellent, and no significant adverse effects were recorded, only transient discomfort. These results show that autologous cytokine-rich serum is a safe and promising alternative, although controlled studies are required to confirm its efficacy.

PMID:
42469099
Bibliographic data and abstract were imported from PubMed on 18 Jul 2026.

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